Turn targets into one-hit punching bags!
Read this description for the explanations of how each target was set up, as well as why other targets couldn't be killed this way.
Tamir
You can't take his heath down early without getting detected, which makes it impossible to progress.
Garnier
Get into the hospital early through the window.
http://thehiddenblade.com/garnier-easy-way-preassassination
Then take down his health until he's one punch away from death.
Talal
After killing his guards, take out Talal's health with throwing knives.
http://thehiddenblade.com/air-assassinate-same-height
You'll need to have done the Garnier assassination first to have the knives unlocked.
Now one punch is all you need to take him out, but it's easy to miss on the running target.
William
Get into his fortress early.
http://thehiddenblade.com/williams-instant-kills-and-king-richards-death
After punching him nearly to death start the scene. Afterward sneak up on him with a jump. If you get detected, William will get into combat stance and block the punch, which happened a lot until I jumped from the spot in the video.
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Many thanks to MAGLX for discovering an easier way of getting in the side window.
setup
The easy way to get inside the hospital early is to to edge jump to the window.
http://thehiddenblade.com/garnier-easy-way-preassassination
After that you will notice Garnier and two guards standing by the door inside the hospital. There are also two other guards and a civilian prestaged for the following cutscene.
Now for the invisible assassination. For those who are not familiar with it, it happens when characters for a scene prior to an assassination are assassinated in high profile (except for the target, he can be assassinated in low profile) while despawning. This causes the memory corridor to start, skipping the assassination mission entirely.
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Hey, guys. Here I find an easy way to climb this window, I believe you just read on to understand how to do it. But I'm not sure whether this method can be used on PS3 & Xbox360, if you had to try this, please tell me whether or not feasible.
http://youtu.be/XdOajd9NCio
[Front-paged. Second video moved below the fold. -stabguy]
Preassassination:
It is possible to get inside Garnier de Naplouse's hospital before you can assassinate him using an exploit. You can get in the broken window by superjumping there (a long range jump). To do this you need a character to air assassinate. So lead a guard to a certain spot and kill him without doing any kill animations. He will still be alive for a short time on the ground, and you can kill him with your hidden blade only. During this time he can be reanimated. To do this find a structure to air assassinate him from. Stand on the other side of the structure, lock on and attempt to assassinate him.
You will bump into the floor of the structure which will cause the air assassinate to fail, but the guard will stand up again and start to walk. He will be unresponsive and won't be affected by gravity which will cause him to airwalk in a straight line. Use this as a way to get in the hospital by trying to get a guard to airwalk to the broken window. I'm not sure if anyone else has found out this exploit (I haven't seen it on youtube so I'm assuming no one has). Once inside the hospital you will find Garnier and two other guards standing by the door. If you kill them they will stay dead for the scene and even afterward. With Garnier already dead there's no way to assassinate him without restarting.
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The Turkey Shoot: The goal in these assassinations is to immobilize the target so that you can easily stab him/her with the hidden blade. Of course, the developers never intended such assassinations to be possible, so you have to rely on several exploits in order to pull off these types of assassinations.
Here are video walkthroughs for the assassinations shown in "The Turkey Shoot".
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Here are some extremes of hiding in plain sight.
William: After William is done lecturing his men, he goes to his desk to study a map. You can climb down behind William and blend right next to him. If you bump into the table, William will notice you, so you need to be careful as you approach the table. In this video, I line up Altair's shoes with William's shoes to ensure that Altair doesn't bump the table.
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Version 2.0 contains updated blitzes of Tamir, Abu'l, Majd, Jubair, Maria, Robert and Al Mualim.
Blitz assassinations of all the main targets. The concept of this style is to assassinate as quickly as possible, while remaining Anonymous before the kill on certain targets: Tamir, Garnier de Naplouse, Abu'l Nuqoud, Majd Addin, William de Montferrat, Jubair Al Hakim and Sibrand.
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A collection of short subjects on Assassin's Creed. Various attempts to do assassinations in ways rumored to be possible/impossible, with mixed results.
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It's recommended that you choose Garnier de Naplouse (Grand Master of the Knights Hospitalier) as your second target because the Throwing Knives and Tackle ability you earn might come in handy when you face Talal. If you've assassinated Garnier before you probably remember being shoved around by mental patients. This guide will show you a cool way to assassinate him without anyone laying a hand on Altaïr.