The Hidden Blade Assassin's Creed in Depth

Turn targets into one-hit punching bags!
Read this description for the explanations of how each target was set up, as well as why other targets couldn't be killed this way.

Tamir

You can't take his heath down early without getting detected, which makes it impossible to progress.

Garnier

Get into the hospital early through the window.
http://thehiddenblade.com/garnier-easy-way-preassassination
Then take down his health until he's one punch away from death.

Talal

After killing his guards, take out Talal's health with throwing knives.
http://thehiddenblade.com/air-assassinate-same-height
You'll need to have done the Garnier assassination first to have the knives unlocked.
Now one punch is all you need to take him out, but it's easy to miss on the running target.

William

Get into his fortress early.
http://thehiddenblade.com/williams-instant-kills-and-king-richards-death
After punching him nearly to death start the scene. Afterward sneak up on him with a jump. If you get detected, William will get into combat stance and block the punch, which happened a lot until I jumped from the spot in the video.

Abul Nuquod

First perform the invisible assassination.
http://thehiddenblade.com/invisible-assassination-abul-nuquod
After that meet up with Abul and take down his health. Then go to one of the city entrances to restart the memory. After doing to mission over again Abul will still have low health, plus his bodyguards won't respawn (not sure if you have to kill them first).

Majd Addin

The problem with this target is he'll detect you if you get him early. I find a way around that, but after doing he mission his health respawned. I remember a guard's health respawns if you reinitialize after detection.

Jubair

Glitch into the Madrasah Al-Kallasah.
http://thehiddenblade.com/jubair-al-hakims-early-death
Kill the remaining guards to become anonymous (you can kill the ones outside the building through the door). Then take down Jubair's health. Make sure you aren't detected by his minions because later on you will desynch after the cutscene.

Sibrand

I thought it could be done, but after taking down his health and heading toward the bureau you desynch with "target escaped" as though you had already started the mission.

Maria

There were some problems. First off when restarting the mission the target walks away from the area until you reach a certain distance. This caused a problem where she was glitched under some stairs. I finally got it to work, but then her health seemed to have respawned.

Robert

There's no way to take down his health before the mission. I could technically do that while fighting his guards, but that would feel cheap.

Al Mualim

No way to take down his health beforehand.