The access codes and Digipens that Desmond can find at Abstergo, and how he can use each one.
Lock 1: Demond's Bedroom Door
The access code in Desmond's closet unlocks the door. Grab it before going to bed in Interlude 3, 4, 5 or 6. At the end of the game the door remains unlocked, even if you never got the access code.
Lock 2: Lucy's computer
Login right in front of Lucy during Interlude 2. Otherwise, use the Digipen that she leaves right next to the computer. This can be done in Interludes 3, 4, 5 or 6, and also after the credits in Interlude 7.
Lock 3: Vidic's computer
Pickpocket the Digipen from Vidic's lab coat whenever he looks out the window. This happens after Desmond wakes up in Interludes 3, 4, 5 and 6. You can also Pickpocket Vidic at any time *during* Memory Blocks 4, 5, 6 or 7. Just don't wait until after the game.
Lock 4: Conference Room Door
Read any of the following emails for the password:
1. Lucy's Outbox (beginning in Interlude 6)
2. Vidic's Deleted Items (beginning in Interlude 6)
3. Vidic's Inbox (beginning in Interlude 5)
The conference room door will only open before Desmond goes to bed in Interlude 6 and again after the credits in Interlude 7.
Lock 5: Conference Room computer
You only need Vidic's Digipen to login.